MARROW-STEM

Bone marrow mesenchymal stem cells aspiration kit

 

MARROW-STEM is an intelligent and effective regenerative solution able to guarantee a short surgical time avoiding any centrifugation which typically takes at least 20 minutes.

MARROW-STEM system is a disposable device for the selective aspiration of mesenchymal cells from the bone marrow which, with its innovative features, optimises the cellular yield and minimises the contamination of peripheral blood thanks to a micrometric system for lateral aspiration and the closed distal tip of the Trocar.

Furthermore, no dedicated staff nor additional time is required to prepare and clean machinery. Complications due to sterility are also minimized by eliminating all additional steps, which are possible sources of infection that then has to be dealt with; in fact, centrifugation systems require marrow aspirate outside the sterile field for processing and reimplantation.

Bone marrow MSCs concentrate can be used to accelerate the natural healing process of the body and can be combined to other kind of bone substitute (homologous, synthetic or xenograft origin) to create an enhanced bone graft. By mixing the selective aspirate of stromal mesenchymal cells with an autologous bone graft, in addition to any synthetic, homologous or xeno bone substitute, the creeping substitution process is accelerated. The resulting graft will be extremely effective, similar to a vascularized graft with high regenerative potential.

FEATURES

  • NO CENTRIFUGATION NEEDED

  • ONLY PURE STEM CELLS AND PROGENITOR CELLS SAMPLING

  • EASY 2-STEP FILTERING

  • REDUCED RISK OF INFECTION

  • STERILE FIELD PROCESSING

BENEFITS

  • No centrifugation required and reduced volume of bone marrow aspiration

  • Ensures sampling of both pure stem cells and progenitor cells at the same time preventing possible contamination from peripheral blood thanks to the closed tip and lateral recruitment

  • Reduced number of surgical steps

  • Allows a single sampling access point to micrometrically collect high-quality bone marrow from multiple sites within the most suitable anatomic sampling region

  • Guarantees multiple multidirectional aspirations from the same sampling site

  • It is suitable for marrow sampling from the anterior and posterior iliac crest, the vertebral body, the tibial plate and the distal femoral access

  • The filter allows marrow purification from oily residues and bone fragments

  • Single-use disposable device

SURGICAL TECHNIQUE

1. Percutaneous access to reach the deepest point in anterior or posterior approach to start aspiration.

2. Micrometric retraction till next aspiration target points.

3. Retraction of the needle and simultaneous aspiration till the proximal target points.

4. Separation from possible contamination of bone fragments, oil and fat using the filtering system provided with the kit.

COMPONENTS

– MARROW-STEM MSCs aspiration device 

ALL-IN-ONE device able to aspirate a high qualitative Bone Marrow MSCs concentrate rich in mesenchymal stem cells, in one surgical session and with a simple and minimally invasive procedure.

LATERAL ASPIRATION and CLOSED DISTAL TIP 

that allows MSCs and not peripheral blood suction

– Mesenchymal Stem Cells filtering device

If necessary, the obtained marrow aspirate can be filtered to remove clots or cellular coagulation or aggregation using the 270-micron purification filter connected to the syringes supplied with the kit

– Selectable and lockable aspiration syringe

The Vaclok syringe provided with the kit allows a controlled bone marrow aspiration.

Injection syringe

VIDEO TUTORIAL

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